teratogen screening: state of the art
نویسندگان
چکیده
due to the number of new substances coming into use every year and the increasing amounts of chemicals, which are introduced into the environment, there is a high demand for a rapid, reliable and cost-effective method for detection of developmental toxicity. to meet this challenge various in vitro techniques have been established additional to in vivo animal testing. this review introduces the techniques in existence at the moment. requirements on an ideal in vitro teratogenicity test system are stated, and the advantages and disadvantages of the present methods are discussed.
منابع مشابه
Teratogen Screening: State of the Art
Due to the number of new substances coming into use every year and the increasing amounts of chemicals, which are introduced into the environment, there is a high demand for a rapid, reliable and cost-effective method for detection of developmental toxicity. To meet this challenge various in vitro techniques have been established additional to in vivo animal testing. This review introduces the ...
متن کاملCervical cancer screening: state of the art.
Screening for cervical cancer, the most common form of cancer in women in most developing countries and the second commonest in women in the world as a whole, presents many challenges. Cervical cancer is preventable and it should be a high priority in all national cancer control programmes. It would seem as though, to be highly effective, various methods warrant joint usage, i.e. cytology with ...
متن کاملEnzyme Immobilization: The State of Art in Biotechnology
The advantages of immobilized enzyme over its soluble counterpart arise from their improved stability andeasy separation from the reaction media, leading to decrease in production cost. Immobilization methodsrange from adsorption onto matrices, entrapment, cross-linking and covalent bonding to prefabricatedcarriers or activated supports. Changes in kinetic properties of immobi...
متن کاملSTATE OF THE ART STATE OF THE ART SERIES Tuberculosis
* International Union Against Tuberculosis and Lung Disease, Paris, France; † Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK; ‡ Operational Research Unit, Medical Department, Brussels Operational Centre, Médecins sans Frontières, Brussels, Belgium; § Institute for Infectious Disease and Molecular Medicine, Desmond Tutu HIV Centre, Facult...
متن کاملState of the Art
Introduction Genetics of Elastase In vitro Substrates of Elastase—Clues to in vivo Function? Regulation and Function of Elastase Inhibition by and Evasion of Antiproteases Elastase Release by Neutrophils Involvement of Elastase in Neutrophil Transvascular Emigration into the Interstitium Membrane-bound Elastase: Vectorial Migration of the Neutrophil? Cytotoxicity and Wound Healing Evidence for ...
متن کاملState of the Art
The Unified Modeling Language (UML) [uml03], [BRJ98], [RJB98], [JBR99] is a modeling language for specifying, visualizing, constructing, and documenting the artifacts of a software-intensive system. It was conceived by three of the most prominent methodologists in the software industry, Grady Booch, James Rumbaugh, and Ivar Jacobson. The language has gained significant industry support from var...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
avicenna journal of medical biotechnologyجلد ۲، شماره ۳، صفحات ۱۱۵-۱۲۱
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023